The Scientifica Neuroscience Learning Zone
The Scientifica neuroscience Learning Zone is a collection of educational resources containing the theoretical and practical knowledge required to perform a variety of experimental techniques related to the hardware we manufacture, focused on their applications in neuroscience research.
It is complemented by Scientifica’s SciMethods; a set of application notes detailing more specific experimental setups, protocols and considerations.
The major topics covered by the Learning Zone include neuronal electrophysiology, microscopy and imaging for neuroscience and photomanipulation for neuroscience.
Neuronal electrophysiology
Electrophysiology is a frequently used method for studying the function of electrically active cells, such as neurons. It encompasses a wide range of techniques from electroencephalograms (EEGs) to single ion-channel recordings. A large amount of the research on the fundamental physiology of neurons and their networks is carried out at a cellular level, and it is these techniques that we concentrate on.
Microscopy & imaging for neuroscience
The development of microscopy revolutionised biology by making many of the minuscule structures responsible for physiological processes visible for the first time. It remains an essential tool in the life sciences and continues to be advanced with the regular conception of new techniques.
The ability to visualise and capture images of the fine structures within tissues using an optical microscope has enabled researchers to uncover the secrets of how cells work and carry out further experimental techniques (e.g. in vitro patch clamp electrophysiology). Several of these techniques are incredibly useful for studying the function of neurons and related cell types.
In neuroscience, advanced imaging methods (e.g. multiphoton microscopy) have facilitated the visualisation of structures deep into brain tissue and with very high temporal and spatial specificity. Further developments have also allowed for a totally optical interrogation of some cellular functions.
Photomanipulation for neuroscience
Credit: Ed Boyden/MIT McGovern Institute
Manipulating the function of cells using light creates an opportunity to elucidate the cause and effect of applying certain experimental conditions. This helps us to understand the physiological function of cells and molecules with high spatial and temporal specificity and with minimal damage to the tissue.
Contribute to the Learning Zone and SciMethods
Scientifica is always working to expand the Learning Zone and SciMethods collections. If you have a related topic that you think we should explore, then please get in touch.
Additionally, if you would like to contribute to or work with us on a Learning Zone topic or SciMethods then please contact us.
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