Molecular Devices Axopatch 200B Amplifier

The benchmark for single-channel recordings and other applications where an excellent signal-to-noise ratio is key

The Axopatch 200B Capacitor Feedback Patch Clamp Amplifier offers one of the lowest-noise single-channel recordings available via innovative capacitor-feedback technology.

For single-channel recording, whole-cell voltage- and current-clamp recordings, extracellular field potential recordings in ion channel, neuroscience, nanopore and voltammetry studies.

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Product benefits

Widely accepted as the gold-standard

For ultra-low noise patch clamp recordings, the Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier is the premier microelectrode amplifier for ultra-low noise patch.

Active headstage cooling

The Axopatch 200B amplifier features proprietary technology that provides active headstage cooling that reduces electrical noise close to the theoretical limits of physics.

Two different speeds to optimise membrane potential recording

It also allows correction for voltage errors due to pipette resistance.

Integrating headstage mode

For measuring sub-picoamp currents to enable high-fidelity single-channel recordings from cell membranes and artificial bilayers.

Slim headstage design

For easier access to the preparation on a crowded microscope stage.

Pipette capacitance compensation

Pipette capacitance compensation neutralises the contribution of the glass pipette and the pipette holder to the capacitance of the circuitry.

Resistive headstage mode

For larger currents and noise levels in whole-cell recordings.

Dual-speed current clamp

Dual-speed current clamp optimises speed and stability through better matching of the clamp algorithm to experimental parameters. Integrated seal test in voltage- and current-clamp mode for easy monitoring of membrane and cell health parameters.