Photometrics Prime 95B Scientific CMOS Camera

Back illuminated sCMOS cameras that offer 95% QE with extreme sensitivity and high frame rates

By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximising light collecting capability. Combining this with large, 11 µm pixels results in a camera technology as sensitive as EMCCD with greater stability, faster speeds and no gain aging.

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Product benefits

Sensitivity

The back-illuminated sCMOS camera achieves a near-perfect 95% quantum efficiency. By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximising light collecting capability. Combining this with large, 11 µm pixels results in camera technology as sensitive as EMCCD with greater stability, faster speeds, and no gain aging.

Superior background quality

The Prime 95B features Pattern Noise Reduction Technology and Correlated Noise Reduction Technology to ensure that it delivers clean, pattern-free images with minimal pixel defects, delivering improved image quality in low light conditions.

Multiple fields of view

The Prime 95B is available with an 18.8, 22 or 25 mm diagonal field of view. The larger format sensors are designed to increase throughput, maximize the amount of data captured and take full advantage of new, larger field of view microscopes.

Features

High peak quantum efficiency

The 95B’s sensor converts up to 95% of incident photons into a measurable signal. Unlike microlens approaches to increasing QE, which lose effectiveness as objective magnification is increased, Prime 95B’s BSI sensor brings light into the pixel photodiode from behind, avoiding structures that reflect or absorb light. When combined with large 11µm pixels, Prime 95B can deliver over 300% more signal than other sCMOS cameras at 100X magnification.

Better than EMCCD

Prime 95B outperforms EMCCD cameras—with no excess noise that negates the benefit of using a high QE sensor, and additional limitations from EM gain calibration, stability, expense, and sensor lifetime. With a true 16-bit dynamic range, Prime 95B easily accomplishes what EMCCD can not—detect weak and bright signals within the same image with photon-noise limited performance.

Extreme Sensitivity

The extreme sensitivity not only allows fainter signals to be detected, it provides the flexibility to increase frame rates, or turn down the excitation intensity to reduce cellular photo-damage. Yet Prime 95B maintains the same high frame rates, field-of-view and extremely low read noise that has made sCMOS so popular for live-cell imaging.

Downloads

Download Prime 95B sCMOS Camera Series datasheets.

Speak to one of our experts for details on pricing, features, installation and support.