The Scientifica SciCam+ Camera
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    Scientifica SciCam+ Camera
    Overview Technical Data
    High-resolution sCMOS camera for patch clamp experiments
    Scientifica SciCam+ camera on electrophysiology rig
    High-resolution sCMOS camera for fluorescent imaging
    Scientifica SciCam+ camera on patch clamp rig
    High-resolution sCMOS camera for Infrared (IR) Differential Interference Contrast (DIC) imaging

    Scientifica SciCam+ Camera

    Visualise high-contrast cells for precise patch clamping and fluorescent imaging, with seamless data capture

    The SciCam+ is a high-resolution sCMOS camera purpose-built to meet the demands of patch clamp electrophysiology. Its fast frame rate and high sensitivity allow for precise electrode positioning and clear visualisation of even the smallest cellular structures.

    Ideal for Infrared (IR) Differential Interference Contrast (DIC) imaging, as well as fluorescence, live cell, and calcium imaging, the SciCam+ delivers high contrast and customisable settings, ensuring accurate data collection and smoother experimental workflows.

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    Product benefits

    Visualise smooth positioning of your electrodes

    The SciCam+ offers a fast frame rate of 40fps across the full frame, providing real-time feedback between the image and your manipulator movement. This ensures precise adjustments without delays, allowing you to position the pipette accurately, even in the most delicate cellular environments.

    Capture fast cellular events in full detail

    The 40fps full-frame speed ensures no critical data is missed. Capture fast, transient signals, such as those in calcium imaging, across the entire field of view. This provides high-resolution insights into neural activity and other rapid biological processes, without sacrificing image size or quality.

    See more at once

    The 18.8mm diagonal field of view allows you to visualise more of the sample at once, making it easier to locate and target specific regions of interest, reducing the need for constant repositioning and improving workflow efficiency.

    Visualise even the smallest detail

    The SciCam+ camera provides high-resolution images, ensuring that even the smallest cellular details are clearly visible, essential for precise pipette positioning and monitoring activity with fine detail.

    High sensitivity at key wavelengths for electrophysiology

    With high sensitivity in both visible and infrared light, the SciCam+ delivers clear, detailed images in a wide range of lighting conditions. This ensures reliable visualisation of cells and structures during patch clamp experiments, even in low-light or infrared imaging setups like IR-DIC.

    Capture even the faintest fluorescent signals

    With just 2.2 e- of readout noise, this camera will capture even the faintest fluorescent signals.

    Built for patch clamping

    You can record even the smallest electrophysiological signals using the SciCam+ camera - the fanless cooling means no vibrations to disturb your sample. In addition, the SciCam+ incorporates a grounding port to offer further opportunities for noise reduction if needed.

    See the sample the way you want too

    Achieve complete control of your image through a range intuitive software including, Mosaic, Micromanager, Labview and MATLAB. Visualise the image as you want it – zoom in, alter contrast, change exposure time.

    Perfect for long-term experiments

    You can record long experiments due to the fanless cooling while retaining high-quality images.

    Simplified setup with USB power

    The SciCam+ camera is powered over USB, eliminating the need for a separate power supply. With just one cable for data transfer and power, your rig is cleaner and easier to manage. Fewer cables also mean less chance of introducing noise, improving the quality of your recordings.

    Maximise your workspace

    The camera's compact design saves valuable space within your Faraday cage, creating an efficient, organised workspace and reducing potential interference with other instruments.

    Record at the right time

    The SciCam+'s trigger inputs and outputs enable perfectly timed recordings and smooth coordination with peripheral equipment during patch clamp experiments.

    Testimonials

    "The SciCam+ combines an exceptional field of view with very high resolution imaging using infra-red and fluorescent imaging modes, whilst being exceptionally quiet and easy to install. The SciCam+ allows for precise targeting of neurons for whole-cell recording simultaneously with very high-quality imaging."

    Sam Booker
    University of Edinburgh

    Images acquired using Scientifica the SciCam+ camera

    Mouse hippocampus was visualised using IR-DIC on the SciCam+ at 40x objective magnification. Sample courtesy of Vincenzo Mastrolia, Kings College London

    Scientifica SciCam+ camera on electrophysiology rig

    Scientifica SciCam+ on patch clamp rig - SliceScope Pro 1000

    Applications

    • Patch Clamp
    • Electrophysiology
    • Tissue slice electrophysiology
    • IR-DIC imaging
    • Fluorescence imaging
    • Calcium imaging
    • Live cell imaging

    Scientifica services for this product

    Free Lab Consultations

    Your Scientifica specialist can help optimise your lab through a free lab consultation, providing advice on the equipment best suited to your planned experiments and lab space.

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    Lab Move Service

    Our lab move service includes the pack down and reinstallation of your electrophysiology or multiphoton imaging system.

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    Installation & Technical Support

    Our installation team can install your system and provide your lab with bespoke training, ensuring your equipment is up and running as soon as possible.

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    Demonstrations

    Scientifica offer product demonstrations, allowing you to ask questions, learn about the multiphoton system and its applications, and see it for yourself.

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    Warranty & Exchange Programme

    Scientifica offer a two-year warranty with all Scientifica manufactured goods and a one-year warranty for third party supplied goods. Giving you peace of mind when purchasing your Scientifica equipment.

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    Speak to one of our experts for details on pricing, features, installation and support.

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