Scientifica SliceScope

Research Papers

• Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons

  Abs, E/. Poorthuis, R B., Apelblat, D., Muhammad, K., Belen Pardi, M., Enke, L., Kushinsky, D., Pu, DL., Ferdinand Eizinger, M., Conzelmann, K K., Spiegel, I., & Letzkus, J. (2018). Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons. Neuron, 100(3), 684-699. https://www.sciencedirect.com/science/article/pii/S0896627318307748#!

• Expression of TRPV1 channels by Cajal-Retzius cells and layer-specific modulation of synaptic transmission by capsaicin in the mouse hippocampus

  Anstotz, M., Lee, S K., & Maccaferri, G. (2018). Expression of TRPV1 channels by Cajal-Retzius cells and layer-specific modulation of synaptic transmission by capsaicin in the mouse hippocampus. The Journal of Physiology, 596(16), 3739 - 3758. https://physoc.onlinelibrary.w...

• Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula

  Ariasm H R., Jin, X., Feuerbach, D., & Drenan, R M. (2017). Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula. The International Journal of Biochemistry & Cell Biology, 92, 202-209. https://www.sciencedirect.com/...

• Photoactivatable drugs for nicotinic optopharmacology

  Banala, S., Arvin, M C., Bannon, N M., Jin, X-T., Macklin, J J., Wang, Y., Peng, C., Zhao, G., Marshall, J J., Gee, K R., Wokosin, D L., Kim, V J., McIntosh, J M., Contractor, A., Lester, H A., Kozorovitskiy, Y., Drenan, R M., Lavis, L D. (2018). Photoactivatable drugs for nicotinic optopharmacology. Nature Methods, 15, 347-350. https://www.nature.com/article...

• Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis

  Bao, H., Asrican, B., Li, W., Deisseroth, K., Philpot, B., & Song, J. (2017). Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis. Cell Stem Cell. 21(5), 604-617. https://www.cell.com/cell-stem...

• A sweet taste receptor-dependent mechanism of glucosensing in hypothalamic tanycytes

  Benford, H., Bolborea, M., Pollatzek, E., Lossow, K., Hermans-Borgmeyer, I., & Liu, B. et al. (2017). A sweet taste receptor-dependent mechanism of glucosensing in hypothalamic tanycytes. Glia, 65(5), 773-789. http://dx.doi.org/10.1002/glia...

• Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex

  Bifari, F., Decimo, I., Pino, A., Llorens-Bobadilla, E., Zhao, S., & Lange, C. et al. (2017). Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex. Cell Stem Cell, 20(3), 360-373.e7. http://dx.doi.org/10.1016/j.st...

• A reconfigurable visual-programming library for real-time closed-loop cellular electrophysiology

  Biró, I., & Giugliano, M. (2015). A reconfigurable visual-programming library for real-time closed-loop cellular electrophysiology. Frontiers In Neuroinformatics, 9. http://dx.doi.org/10.3389/fnin...

• Brain‐derived neurotrophic factor acts at neurons of the subfornical organ to influence cardiovascular function

  Black, E A E., Smith, P M., McIsaac, W., & Ferguson, A V. (2018). Brain‐derived neurotrophic factor acts at neurons of the subfornical organ to influence cardiovascular function. Physiological Reports, 6(10. https://physoc.onlinelibrary.w...

• Profound Desensitization by Ambient GABA Limits Activation of -Containing GABAA Receptors during Spillover

  Bright, D., Renzi, M., Bartram, J., McGee, T., MacKenzie, G., & Hosie, A. et al. (2011). Profound Desensitization by Ambient GABA Limits Activation of -Containing GABAA Receptors during Spillover. Journal Of Neuroscience, 31(2), 753-763. http://dx.doi.org/10.1523/jneu...

• A molecular census of arcuate hypothalamus and median eminence cell types

  Campbell, J., Macosko, E., Fenselau, H., Pers, T., Lyubetskaya, A., & Tenen, D. et al. (2017). A molecular census of arcuate hypothalamus and median eminence cell types. Nature Neuroscience, 20(3), 484-496. http://dx.doi.org/10.1038/nn.4...

• Two-Photon Holographic Stimulation of ReaChR

  Chaigneau, E., Ronzitti, E., Gajowa, A M., Soler-Llavina, G J., Tanese, D., Brureau, A Y B., Papagiakoumou, P., Zeng, H., & Emiliani, V. (2016). Two-Photon Holographic Stimulation of ReaChR. Frontiers in Cellular Neuroscience. https://www.frontiersin.org/articles/10.3389/fncel.2016.00234/full

• Concurrent activation of striatal direct and indirect pathways during action initiation

  Cui, G., Jun, S., Jin, X., Pham, M., Vogel, S., Lovinger, D., & Costa, R. (2013). Concurrent activation of striatal direct and indirect pathways during action initiation. Nature, 494(7436), 238-242. http://dx.doi.org/10.1038/natu...

• Altered CO2 sensitivity of connexin26 mutant hemichannels in vitro

  de Wolf, E., van de Wiel, J., Cook, J., & Dale, N. (2016). Altered CO2 sensitivity of connexin26 mutant hemichannels in vitro. Physiological Reports, 4(22), e13038. http://dx.doi.org/10.14814/phy...

• Reducing Extracellular Ca2+ Induces Adenosine Release via Equilibrative Nucleoside Transporters to Provide Negative Feedback Control of Activity in the Hippocampus

  Diez, R., Richardson, M J E., & Wall, MJ. (2017). Reducing Extracellular Ca2+ Induces Adenosine Release via Equilibrative Nucleoside Transporters to Provide Negative Feedback Control of Activity in the Hippocampus. Frontiers in Neural Circuits. https://www.frontiersin.org/ar...

• Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake

  D'Agostino, G., Lyons, D., Cristiano, C., Lettieri, M., Olarte-Sanchez, C., Burke, L K., Greenwald-Yarnell, M., Cansell, C., Doslikova, B., Georgescu, T/. Martinez de Morentin, P B., Myers Jr, M G., Rochford, J J., & Heisler, L K. (2018). Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake. Cell Metabolism, 28(4), 619 - 630. https://www.sciencedirect.com/science/article/pii/S1550413118304601#!

• A synaptic threshold mechanism for computing escape decisions

  Evans, D A., Stempel, A V., Vale, R., Ruehle, S., Lefler, Y., & Branco, T. (2018). A synaptic threshold mechanism for computing escape decisions. Nature, 558. https://www.nature.com/article...

• A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH

  Fenselau, H., Campbell, J., Verstegen, A., Madara, J., Xu, J., & Shah, B. et al. (2016). A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH. Nature Neuroscience, 20(1), 42-51. http://dx.doi.org/10.1038/nn.4...

• A novel multisite confocal system for rapid Ca2+ imaging from submicron structures in brain slices

  Filipis, L., Quares, K A., Moreau, P., Tanese, D., Zampini, V., Latini, A., Bleau, C., Bleau, C., Graham, J., & Canepari, M. (2017). A novel multisite confocal system for rapid Ca2+ imaging from submicron structures in brain slices. Journal of Biophotonics. https://onlinelibrary.wiley.co...

• Region-specific and state-dependent action of striatal GABAergic interneurons

  Fino, E., Vandecasteele, M., Perez, S., Saudou, F., & Venance, L. (2018). Region-specific and state-dependent action of striatal GABAergic interneurons. Nature Communications, 3339(9). https://www.nature.com/article...

• Prefrontal cortical control of a brainstem social behavior circuit

  Franklin, T., Silva, B., Perova, Z., Marrone, L., Masferrer, M., & Zhan, Y. et al. (2017). Prefrontal cortical control of a brainstem social behavior circuit. Nature Neuroscience, 20(2), 260-270. http://dx.doi.org/10.1038/nn.4...

• Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B

  Jiang, Y., Jakovcevski, M., Bharadwaj, R., Connor, C., Schroeder, F., & Lin, C. et al. (2010). Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B. Journal Of Neuroscience, 30(21), 7152-7167. http://dx.doi.org/10.1523/jneu...

• Blue light responses in Cancer borealis stomatogastric ganglion neurons.

  Kedia, S. & Marder, E. (2022). Blue light responses in Cancer borealis stomatogastric ganglion neurons. Current Biology, 32(6), 1439-1445. https://doi.org/10.1016/j.cub.2022.01.064

• HCN4 pacemaker channels attenuate the parasympatheticresponse and stabilize the spontaneous firing of the sinoatrial node

  Kozasa, Y., Nakashima, N., Ito, M., Ishikawa, T., Kimoto, H., Ushijima, K., Makita, N., & Takono, M. (2018). HCN4 pacemaker channels attenuate the parasympatheticresponse and stabilize the spontaneous firing of the sinoatrial node. The Journal of Physiology. 596(5), 809-825. https://physoc.onlinelibrary.w...

• Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5

  Lalanne, T., Oyrer, J., Mancino, A., Gregor, E., Chung, A., & Huynh, L. et al. (2015). Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5. The Journal Of Physiology, 594(4), 837-861. http://dx.doi.org/10.1113/jp27...

• Dynamical response properties of neocortical neurons to conductance-driven time-varying inputs

  Linaro, D., Biro, I., & Giugliano, M. (2018). Dynamical response properties of neocortical neurons to conductance-driven time-varying inputs. European Journal of Neuroscience, 47, 17-32. https://onlinelibrary.wiley.co...

• Firing properties of entorhinal cortex neurons and early alterations in an Alzheimer's disease transgenic model

  Marcantoni, A., Raymond, E., Carbone, E., & Marie, H. (2013). Firing properties of entorhinal cortex neurons and early alterations in an Alzheimer's disease transgenic model. Pflügers Archiv - European Journal Of Physiology, 466(7), 1437-1450. http://dx.doi.org/10.1007/s004...

• High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

  Mager, T., Lopez de la Morena, D., Senn, V., Schlotte, J., D'Errico, A., Feldbauer, K., Wrobel, C., Jung, S., Bodensiek, K., Rankovic, V., Browne, L., Huet, A., Juttner, J., Wood, P G., Letzkus, J J., Moser, T., & Bamberg, E. (2018). High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics. Nature Communications, 9. https://www.nature.com/article...

• CO2directly modulates connexin 26 by formation of carbamate bridges between subunits

  Meigh, L., Greenhalgh, S., Rodgers, T., Cann, M., Roper, D., & Dale, N. (2013). CO2directly modulates connexin 26 by formation of carbamate bridges between subunits. Elife, 2. http://dx.doi.org/10.7554/elif...

• Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function

  Mittal, N., Minasyan, A.,Romaneschi, N., Hakimian, J K., Gonzalez-Fernandez, G., Albert, R., Desai, N., Mendez, I A., Schallert, T., Ostlund, S B., & Walwyn, W. (2017). Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function. PLOS ONE. https://journals.plos.org/plos...

• Panic results in unique molecular and network changes in the amygdala that facilitate fear responses

  Molosh, A I., Dustrude, E T., Lukkes, J L., Fitz, S D., Caliman, I F., Abreu, A R R., Dietrich, A D., Truitt, W A., Ver Donck, L., Ceusters, M., Kent, J M., Johnson, P L., & Shekhar, A. (2018). Panic results in unique molecular and network changes in the amygdala that facilitate fear responses. Molecular Psychiatry. https://www.nature.com/article...

• Random-access scanning microscopy for 3D imaging in awake behaving animals

  Nadella, K., Roš, H., Baragli, C., Griffiths, V., Konstantinou, G., & Koimtzis, T. et al. (2016). Random-access scanning microscopy for 3D imaging in awake behaving animals. Nature Methods, 13(12), 1001-1004. http://dx.doi.org/10.1038/nmet...

• Mapping of excitatory and inhibitory postsynaptic potentials of neuronal populations in hippocampal slices using the GEVI, ArcLight

  Nakajima, R., & Baker, B J/ (2018). Mapping of excitatory and inhibitory postsynaptic potentials of neuronal populations in hippocampal slices using the GEVI, ArcLight. Journal of Physics D: Applied Physics, 51. https://iopscience.iop.org/art...

• RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling

  Ostrovskaya, O., Xie, K., Masuho, I., Fajardo-Serrano, A., Lujan, R., Wickman, K., & Martemyanov, K. (2014). RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. Elife, 3. http://dx.doi.org/10.7554/elif...

• Gene editing vectors for studying nicotinic acetylcholine receptors in cholinergic transmission

  Peng, C., Yan, Y., Kim, K J., Eagle, S E., Berry, J N., McIntosh, M., Neve, R L., Drenan, R M. (2018). Gene editing vectors for studying nicotinic acetylcholine receptors in cholinergic transmission. European Journal of Neuroscience. https://onlinelibrary.wiley.co...

• Tailoring light delivery for optogenetics by modal demultiplexing in tapered optical fibers

  Pisanello, M., Pisano, F., Sileo, L., Maglie, E., Bellistri, E., Spagnolo, B., Mandelbaum, G., Sabatini, B L., Vittorio, M D., & Pisanello, F. (2018). Tailoring light delivery for optogenetics by modal demultiplexing in tapered optical fibers. Scientific Reports, 8(4467). https://www.nature.com/article...

• Marked bias towards spontaneous synaptic inhibition distinguishes non-adapting from adapting layer 5 pyramidal neurons in the barrel cortex

  Popescu, I R., Le, K Q., Palenzuela, R., Voglewede, R., & Mostany, R. (2017). Marked bias towards spontaneous synaptic inhibition distinguishes non-adapting from adapting layer 5 pyramidal neurons in the barrel cortex. Scientific Reports, 7. https://www.nature.com/article...

• Laser micromachining of tapered optical fibers for spatially selective control of neural activity

  Rizzo, A., Domencio Lemme, E., Pisano, F., Pisanello, M., Sileo, L., De Vittorio, M., & Pisanello, F. (2018). Laser micromachining of tapered optical fibers for spatially selective control of neural activity. Microelectric Engineering, 192, 89-95. https://www.sciencedirect.com/science/article/pii/S0167931718300698#!

• Differential toxicity of TAR DNA‐binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells

  Salvatori, I., Ferri, A., Scaricamazza, S., Giovannelli, I., Serrano, A., Rossi, S., D'Ambrosi, N., Cozzolino, M., Di Giullio, A., Moreno, S., Valle, C., & Carri, M T. (2018). Differential toxicity of TAR DNA‐binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells. Journal of Neurochemistry, 146(5), 585 - 597. https://www.scientifica.uk.com...

• Interaction of Intrinsic and Synaptic Currents Mediate Network Resonance Driven by Layer V Pyramidal Cells

  Schmidt, S L., Dorsett, C R., Iyengar, A P., & Fröhlich, F. (2016). Interaction of Intrinsic and Synaptic Currents Mediate Network Resonance Driven by Layer V Pyramidal Cells. Cerebral Cortex, 27(9), 4396-4410. https://academic.oup.com/cercor/article/27/9/4396/3056464

• Evolution of a central neural circuit underlies Drosophila mate preferences

  Seeholzer, L F., Seppo, M., Stern, D L., & Ruta, V. (2018). Evolution of a central neural circuit underlies Drosophila mate preferences. Nature, 559, 564-569. https://www.nature.com/article...

• High-speed volumetric imaging of neuronal activity in freely moving rodents

  Skocek, O., Nobauer, T., Weilguny, L., Marinez Traub, F., Xia, C N., Molodtsov, M I., Grama, A., Yamagata, M., Aharoni, D., Cox, D D., Golshani, P., & Vaziri, A. (2018). High-speed volumetric imaging of neuronal activity in freely moving rodents. Nature Methods, 15. 429 - 432. https://www.nature.com/article...

• A calcium-dependent pathway underlies activity-dependent plasticity of electrical synapses in the thalamic reticular nucleus

  Sevetson, J., Fittro, S., Heckman, E., & Haas, J. (2017). A calcium-dependent pathway underlies activity-dependent plasticity of electrical synapses in the thalamic reticular nucleus. The Journal Of Physiology. http://dx.doi.org/10.1113/jp27...

• Temporally precise single-cell-resolution optogenetics

  Shemesh, O A., Tanese, D., Zampini, V., Linghu, C., Piatkevich, K., Ronzitti, E., Papagiakoumou, E., Boyden, E S., & Emiliani, V. (2017). Temporally precise single-cell-resolution optogenetics. Nature Neuroscience, 20, 1796-1806. https://www.nature.com/article...

• BH4 domain peptides derived from Bcl-2/Bcl-XL as novel tools against acute pancreatitis

  Vervliet, T., Gerasimenko, J V., Ferdek, P E., Jakubowska, M A., Petersen, O H., Gerasimenko, O V., & Bultynck, G. (2018). BH4 domain peptides derived from Bcl-2/Bcl-XL as novel tools against acute pancreatitis. Cell Death Discovery, 4(58), https://www.ncbi.nlm.nih.gov/p...

• Corticosterone Induces Rapid Increase in the Amplitude of Inhibitory Response in Hippocampal Synapses with Asynchronous GABA Release

  Volkova, E., Rozov, A., Nadareishvili, G., & Bol’shakov, A. (2016). Corticosterone Induces Rapid Increase in the Amplitude of Inhibitory Response in Hippocampal Synapses with Asynchronous GABA Release. Bulletin Of Experimental Biology And Medicine, 160(5), 628-631. http://dx.doi.org/10.1007/s105...

• η-Secretase processing of APP inhibits neuronal activity in the hippocampus

  Willem, M., Tahirovic, S., Busche, M., Ovsepian, S., Chafai, M., & Kootar, S. et al. (2015). η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature, 526(7573), 443-447. http://dx.doi.org/10.1038/natu...

• Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways

  Yeh, C-Y., Asrican, B., Moss, J., Quintanilla, LJ., He, T., Mao, X., Cassé, F., Gebara, E., Bao, H., Lu, W., Toni, N., & Song, J. (2018). Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways. Neuron, 99(3), 493 - 510. https://www.sciencedirect.com/science/article/pii/S0896627318305841#!

• Maturation and circuit integration of transplanted human cortical organoids.

  Revah, O., Gore, F., Kelley, K.W. et al. Maturation and circuit integration of transplanted human cortical organoids. Nature 610, 319–326 (2022). https://doi.org/10.1038/s41586...

• Functionally distinct circuits are linked by heterocellular electrical synapses in the thalamic reticular nucleus

  Vaughn, M.J. et al. (2023) 'Functionally distinct circuits are linked by heterocellular electrical synapses in the thalamic reticular nucleus,' ENeuro, p. ENEURO.0269-23.2023. https://doi.org/10.1523/eneuro...