Scientifica SliceScope Pro 2000
Standard System
We can customise this system to suit your unique experimental needs. Please contact us to discuss your requirements.
Slimline fully motorised microscope
Choose from Scientifica PatchStars or MicroStars
50mm of travel
Large mounting stage for sample & manipulators
Choose from the Scientifica PatchPad or Control Cube
Recording chamber & perfusion tools
Accessories
Collect higher quality data across the entire field of view with the Scientifica Filter Cube Module (FCM).
High resolution CCD camera specifically designed for use with electrophysiology setups. It is ideal for fluorescence imaging, live cell imaging, calcium imaging and electrophysiology.
The Scientifica Motorised Objective Changer can change smoothly between two objectives and display within LinLab which objective is in position. The user has full control over the speed of objective exchange.
Research Papers
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Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling
Benevento, M., Iacono, G., Selten, M., Ba, W., Oudakker, A., & Frega, M. et al. (2016). Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling. Neuron, 91(2), 341-355. http://dx.doi.org/10.1016/j.ne...
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Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval
Beyeler, A., Namburi, P., Glober, G., Simonnet, C., Calhoon, G., & Conyers, G. et al. (2016). Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval. Neuron, 90(2), 348-361. http://dx.doi.org/10.1016/j.ne...
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Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment
Burgos-Robles, A., Kimchi, E., Izadmehr, E., Porzenheim, M., Ramos-Guasp, W., & Nieh, E. et al. (2017). Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment. Nature Neuroscience. http://dx.doi.org/10.1038/nn.4...
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Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch
Dehorter, N., Ciceri, G., Bartolini, G., Lim, L., del Pino, I., & Marin, O. (2015). Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch. Science, 349(6253), 1216-1220. http://dx.doi.org/10.1126/scie...
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Marking cells with infrared fluorescent proteins to preserve photoresponsiveness in the retina
Fyk-Kolodziej, B., Hellmer, C., & Ichinose, T. (2014). Marking cells with infrared fluorescent proteins to preserve photoresponsiveness in the retina. Biotechniques, 57(5). http://dx.doi.org/10.2144/0001...
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A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina
Hellmer, C., Clemons, M., Nawy, S., & Ichinose, T. (2018). A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina. Physiological Reports. https://physoc.onlinelibrary.w...
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Morphological and physiological analysis of type-5 and other bipolar cells in the Mouse Retina
Hellmer, C., Zhou, Y., Fyk-Kolodziej, B., Hu, Z., & Ichinose, T. (2016). Morphological and physiological analysis of type-5 and other bipolar cells in the Mouse Retina. Neuroscience, 315, 246-258. http://dx.doi.org/10.1016/j.ne...
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Dopaminergic Modulation of Signal Processing in a Subset of Retinal Bipolar Cells
Hellmer, C., Bohl, J., Hall, L., Koehler, C., & Ichinoise, T. (2020). Dopaminergic Modulation of Signal Processing in a Subset of Retinal Bipolar Cells. Frontiers in Cellular Neuroscience. https://doi.org/10.3389/fncel.2020.00253
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Differential signalling and glutamate receptor compositions in the OFF bipolar cell types in the mouse retina
Ichinose, T., & Hellmer, C. (2015). Differential signalling and glutamate receptor compositions in the OFF bipolar cell types in the mouse retina. The Journal Of Physiology, 594(4), 883-894. http://dx.doi.org/10.1113/jp27...
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Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina
Ichinose, T., Farshi, P., Fyk-Kolodziej, B., Krolewski, D., & Walker, P. (2015). Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina. The Journal Of Comparative Neurology, 524(10). Retrieved from http://onlinelibrary.wiley.com...
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Roles of ON Cone Bipolar Cell Subtypes in Temporal Coding in the Mouse Retina
Ichinose, T., Fyk-Kolodziej, B., & Cohn, J. (2014). Roles of ON Cone Bipolar Cell Subtypes in Temporal Coding in the Mouse Retina. Journal Of Neuroscience, 34(26), 8761-8771. http://dx.doi.org/10.1523/jneu...
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ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons
Pougnet, J., Toulme, E., Martinez, A., Choquet, D., Hosy, E., & Boué-Grabot, E. (2014). ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons. Neuron, 83(2), 417-430. http://dx.doi.org/10.1016/j.ne...
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Age-dependent changes of photosynthetic responses induced by electrical signals in wheat seedlings
Vodeneev, V., Sherstneva, O., Surova, L., Semina, M., Katicheva, L., & Sukhov, V. (2016). Age-dependent changes of photosynthetic responses induced by electrical signals in wheat seedlings. Russian Journal Of Plant Physiology, 63(6), 861-868. http://dx.doi.org/10.1134/s102...
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Glucose concentrations modulate brain‐derived neurotrophic factor responsiveness of neurones in the paraventricular nucleus of the hypothalamus
McIsaac, W., Ferguson, A V. (2017). Glucose concentrations modulate brain‐derived neurotrophic factor responsiveness of neurones in the paraventricular nucleus of the hypothalamus. Journal of Neuroendocrinology, 29(4). https://onlinelibrary.wiley.com/doi/full/10.1111/jne.12464